Description

Human Insulin-Like-Growth-Factor-I (21-40) is a synthetic peptide fragment corresponding to residues 21-40 of the full-length IGF-I protein. This high-purity peptide is a critical research tool for studying the structure-activity relationships and biological functions of IGF-I, a key regulator of cell growth, proliferation, and differentiation. It is essential for biochemical research, pharmaceutical development, and as a reference standard in analytical laboratories focusing on metabolic and growth factor studies.

Application

• Biochemical Research: Used as a specific antigen for antibody production and characterization in immunological assays.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of IGF-I-based therapeutics and diagnostic kits.
• Structure-Activity Relationship (SAR) Studies: Critical for mapping the bioactive regions of the full IGF-I hormone to understand receptor binding and signaling mechanisms.
• Analytical Standard: Employed as a high-purity calibrant in chromatographic (HPLC, LC-MS) and spectroscopic analyses for quality control and method validation.
• Cell Culture & In Vitro Studies: Used in controlled experiments to investigate the specific effects of the IGF-I (21-40) domain on cell proliferation and metabolism.

Basic Information

Product Name	Human Insulin-Like-Growth-Factor-I (21-40)
CAS No.	141472-16-4
Molecular Formula	C94H150N28O27
Molecular Weight	2152.4 g/mol
Synonyms	IGF-I (21-40); Insulin-like growth factor I (21-40); Somatomedin C (21-40); IGF-I fragment 21-40; hIGF-I (21-40); IGF1 (21-40); [Des-Ala1-Tyr24-Leu25-Tyr31]-IGF-I (21-40) (sequence-based); Synthetic IGF-I peptide (21-40)
EINECS	Contact for details

Quality Control

Our Human Insulin-Like-Growth-Factor-I (21-40) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with rigorous research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.