Description

Synaptotagmin Ii CAS NO 141440-89-3 is a specialized protein involved in the regulation of synaptic vesicle exocytosis and neurotransmitter release. This compound is of significant value in advanced neuroscience research and drug discovery for neurological disorders. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focusing on synaptic function, membrane trafficking, and neuropharmacology.

Application

• Neuroscience Research: A critical reagent for studying the molecular mechanisms of synaptic transmission, vesicle fusion, and calcium-triggered exocytosis.
• Drug Discovery & Development: Used as a target or tool compound in high-throughput screening (HTS) assays to identify novel therapeutics for neurodegenerative diseases (e.g., Alzheimer's, Parkinson's) and psychiatric conditions.
• Biochemical Assays: Employed in in vitro binding studies, protein-protein interaction analyses, and enzymatic activity tests to elucidate synaptic protein networks.
• Diagnostic Development: Serves as a potential antigen or standard in the development of immunoassays and diagnostic kits for neurological biomarkers.
• Academic & Institutional Research: Essential for fundamental research in cell biology, neurobiology, and molecular physiology to understand neuronal communication.

Basic Information

Product Name	Synaptotagmin Ii
CAS No.	141440-89-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Synaptotagmin-2; Syt2; Synaptotagmin II; Calcium sensor protein Syt2; Synaptotagmin 2; p65; Synaptotagmin II (rat); Synaptotagmin-2 protein
EINECS	Contact for details

Quality Control

Our Synaptotagmin Ii is produced and handled under stringent quality management systems. Each batch undergoes rigorous analytical testing, including purity assessment by HPLC and identity confirmation, to ensure consistency and reliability for research applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90%
Biological Activity	Assay-dependent; contact for details
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.