Description

Cyclobutanecarbonitrile, 2-Acetyl-3,3-Dimethyl-, cis- (9Ci) is a specialized, high-purity organic nitrile building block with a unique sterically hindered cyclobutane structure. This compound is valued for its role as a key chiral intermediate in the synthesis of complex pharmaceutical molecules and advanced materials. It is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its complex ring system for bioactivity.
• Fine Chemical Production: Serves as a versatile building block for synthesizing specialty chemicals, flavors, fragrances, and advanced polymers.
• Academic & Industrial Research: Employed in chemical research for methodology development, catalysis studies, and exploring new reaction pathways.
• Material Science: Potential precursor for developing specialty monomers or ligands used in catalyst design and functional materials.

Basic Information

Item	Detail
Product Name	Cyclobutanecarbonitrile, 2-Acetyl-3,3-Dimethyl-, cis- (9Ci)
CAS No.	141422-99-3
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	cis-2-Acetyl-3,3-dimethylcyclobutanecarbonitrile; (1S,2R)-2-Acetyl-3,3-dimethylcyclobutanecarbonitrile; 2-Acetyl-3,3-dimethylcyclobutanecarbonitrile (cis-); 141422-99-3; Cyclobutanecarbonitrile, 2-acetyl-3,3-dimethyl-, (1S,2R)-rel-; ACDMCBCN
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonitrile, 2-Acetyl-3,3-Dimethyl-, cis- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the exacting standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.