Description

Cyclobutanecarbonitrile, 3-Acetyl-2,2-Dimethyl-, trans- (9Ci) is a specialized organic nitrile building block featuring a rigid cyclobutane ring and an acetyl functional group. This compound matters as a high-value intermediate for synthesizing complex molecules, offering a unique stereochemical and structural framework for advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for creating novel active ingredients, as well as by fine chemical manufacturers producing custom intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for creating molecules with constrained geometries.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the cyclobutane core contributes to specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Investigated as a monomer or building block for specialty polymers with unique thermal or mechanical properties.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for bespoke chemical entities.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including ring-opening and functionalization reactions.

Basic Information

Product Name	Cyclobutanecarbonitrile, 3-Acetyl-2,2-Dimethyl-, trans- (9Ci)
CAS No.	141422-98-2
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	trans-3-Acetyl-2,2-dimethylcyclobutanecarbonitrile; (1R,3S)-3-Acetyl-2,2-dimethylcyclobutanecarbonitrile; 2,2-Dimethyl-3-oxocyclobutanecarbonitrile (related); 3-Acetyl-2,2-dimethylcyclobutanecarbonitrile; trans-2,2-Dimethyl-3-acetylcyclobutanecarbonitrile; Cyclobutanecarbonitrile, 3-acetyl-2,2-dimethyl-, trans-; (1S,3R)-3-Acetyl-2,2-dimethylcyclobutanecarbonitrile (enantiomer)
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonitrile, 3-Acetyl-2,2-Dimethyl-, trans- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.