Description

Cyclopentanecarboxylic Acid, 1-Fluoro-2-Oxo-, Methyl Ester (9Ci) is a high-purity fluorinated organic building block, specifically a methyl ester derivative of a functionalized cyclopentane ring. This compound is valued for its unique molecular architecture, combining a constrained five-membered ring with both a fluorine atom and a keto-ester moiety, making it a versatile synthon for advanced chemical synthesis. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, such as active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those requiring fluorinated cyclopentane scaffolds to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorinated ring structure can enhance biological activity and environmental profile.
• Advanced Material Synthesis: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials that benefit from its specific steric and electronic properties.
• Chemical Biology & Proteomics: Can be utilized as a reactive handle or a tag in the design of chemical probes for studying enzyme mechanisms or protein interactions.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial R&D: Employed in exploratory chemistry for methodological development and the discovery of new reactions involving fluorinated, strained-ring systems.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 1-Fluoro-2-Oxo-, Methyl Ester (9Ci)
CAS No.	141420-01-1
Molecular Formula	C7H9FO3
Molecular Weight	160.14 g/mol
Synonyms	Methyl 1-fluoro-2-oxocyclopentanecarboxylate; 1-Fluoro-2-oxocyclopentanecarboxylic acid methyl ester; Methyl 1-fluoro-2-oxocyclopentane-1-carboxylate; Cyclopentanecarboxylic acid, 1-fluoro-2-oxo-, methyl ester; (1-Fluoro-2-oxocyclopentyl)carboxylic acid methyl ester; Fluorinated cyclopentane keto-ester; 141420-01-1 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 1-Fluoro-2-Oxo-, Methyl Ester (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the exacting standards of research and process chemistry. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced applications and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. Handle and store under an inert atmosphere if specified for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.