Description

Hiv-1 Rev Protein (34-50) is a synthetic peptide fragment corresponding to a specific region of the HIV-1 Rev regulatory protein. This high-purity peptide is a critical research reagent for studying viral replication mechanisms, protein-protein interactions, and the development of novel antiviral strategies. It is essential for molecular biologists, virologists, and pharmaceutical researchers engaged in HIV/AIDS research, drug discovery, and diagnostic assay development.

Application

• Biochemical Research: Used as a key reagent in studies of Rev protein function, nuclear export of viral RNA, and HIV-1 replication cycles.
• Antiviral Drug Discovery: Serves as a target or competitor in high-throughput screening assays to identify and characterize novel inhibitors of Rev-mediated pathways.
• Antibody Production & Epitope Mapping: Employed as an immunogen to generate specific antibodies or to map binding sites of existing antibodies targeting the Rev protein.
• Diagnostic Development: Utilized in the development and validation of ELISA, Western blot, or other immunoassays for HIV research and detection.
• Protein Interaction Studies: Acts as a probe in pull-down assays, surface plasmon resonance (SPR), or isothermal titration calorimetry (ITC) to investigate interactions with cellular factors.
• Cell Biology & Imaging: Can be labeled with fluorescent tags for cellular localization studies and visualization of Rev dynamics.

Basic Information

Item	Detail
Product Name	Hiv-1 Rev Protein (34-50)
CAS No.	141237-50-5
Molecular Formula	C78H128N24O22S
Molecular Weight	1761.1 g/mol
Synonyms	HIV-1 Rev (34-50); Rev Peptide (34-50); HIV-1 Regulatory Protein Rev Fragment; TRQARRNRRRRWRERQR; Hiv1 Rev Protein fragment 34-50; Arg-rich motif of HIV-1 Rev; HIV-1 Rev Nuclear Localization Signal Peptide
EINECS	Contact for details

Quality Control

Our Hiv-1 Rev Protein (34-50) is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and Mass Spectrometry (MS) for identity confirmation. A detailed Certificate of Analysis (COA) is provided, documenting purity, amino acid analysis, and other critical quality attributes to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Within ±10% of theoretical values
Peptide Content	≥ 70% (by weight)
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.