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7-(2-(2-Aminothiazol-4-Yl)- 2-(1-Carboxyl-1-Methylethoxyimino)Acetamido)-3-(3-(3,4-Dihydroxybenzoyloxy)-1-Propen-1-Yl)-3-Cephem-4-Carboxylic Acid CAS NO 141197-54-8
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CAS No.:141197-54-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
7-(2-(2-Aminothiazol-4-Yl)- 2-(1-Carboxyl-1-Methylethoxyimino)Acetamido)-3-(3-(3,4-Dihydroxybenzoyloxy)-1-Propen-1-Yl)-3-Cephem-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the cephalosporin class of β-lactam antibiotics. This compound is critical for the synthesis of next-generation antibiotics, offering a sophisticated chemical scaffold for targeting resistant bacterial strains. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel anti-infective therapies and fine chemical synthesis.
Application
- Pharmaceutical Intermediate: Key building block for the synthesis of advanced cephalosporin antibiotic APIs (Active Pharmaceutical Ingredients).
- Antibiotic Research & Development: Used in medicinal chemistry for creating new analogs with improved efficacy against drug-resistant bacteria.
- Fine Chemical Synthesis: Serves as a complex chiral precursor in multi-step organic syntheses for specialized chemical products.
- Biochemical Studies: Employed in research to study β-lactamase inhibition mechanisms and bacterial cell wall synthesis.
- GMP Manufacturing: Supplied as a critical raw material under controlled conditions for cGMP-compliant drug production.
- Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.
Basic Information
| Item | Details |
|---|---|
| Product Name | 7-(2-(2-Aminothiazol-4-Yl)- 2-(1-Carboxyl-1-Methylethoxyimino)Acetamido)-3-(3-(3,4-Dihydroxybenzoyloxy)-1-Propen-1-Yl)-3-Cephem-4-Carboxylic Acid |
| CAS No. | 141197-54-8 |
| Molecular Formula | C24H23N5O10S |
| Molecular Weight | 573.54 g/mol |
| Synonyms | 7-(2-(2-Aminothiazol-4-yl)-2-((1-carboxy-1-methylethoxy)imino)acetamido)-3-((3-(3,4-dihydroxybenzoyloxy)-1-propen-1-yl)-3-cephem-4-carboxylic acid; Cefcapene Pivoxil Intermediate; Cefcapene Pivoxil Related Compound; (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-3-[(E)-3-(3,4-dihydroxybenzoyloxy)prop-1-enyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefcapene Acid; CPM-IA; FR-115752 |
| EINECS | Contact for details |
Quality Control
Our production of this advanced intermediate adheres to stringent quality systems suitable for pharmaceutical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Quality assurance protocols are designed to meet the expectations of cGMP and ICH Q7 guidelines for active pharmaceutical ingredients, ensuring traceability and consistency for critical R&D and manufacturing use.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency. Long-term storage recommendations are available upon request.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 1.0% |
| Related Substances (HPLC) | Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5% |
| Residual Solvents (GC) | Complies with ICH Q3C guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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