Description

Boc-D-Serine Benzylamide is a high-purity, non-natural amino acid derivative featuring orthogonal protecting groups. This compound is a critical chiral building block for the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of peptide-based drugs and bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-serine residues with protected side chains.
• Protease Inhibitor Development: Serves as a core structure in designing inhibitors for various enzymatic targets.
• Chemical Biology Research: Employed in the study of peptide conformation, stability, and receptor interaction.
• GPCR Ligand Synthesis: Building block for peptides targeting G-protein-coupled receptors (GPCRs).
• Antibiotic Research: Used in the synthesis of novel antimicrobial peptides (AMPs).

Basic Information

Product Name	Boc-D-Serine Benzylamide
CAS No.	141108-78-3
Molecular Formula	C15H22N2O4
Molecular Weight	294.35 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-serine benzylamide; Boc-D-Ser-Bn; (2R)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-3-hydroxy-N-benzylpropanamide; tert-Butyloxycarbonyl-D-serine benzylamide; Boc-D-Ser-NH-Bzl; D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, benzylamide; Boc-D-Ser-NHBn
EINECS	Contact for details

Quality Control

Our Boc-D-Serine Benzylamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.