Description

Major Capsid Protein, 142 Kda, Pseudorabies Virus is a highly purified, recombinant viral structural protein essential for virology research and vaccine development. This protein serves as a critical antigen and model for studying herpesvirus architecture, immunogenicity, and host-pathogen interactions. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in antiviral drug discovery, diagnostic assay development, and next-generation veterinary vaccine formulation.

Application

• Vaccine Research & Development: Key antigen for the development and immunogenicity testing of pseudorabies virus (PRV) and related herpesvirus vaccines.
• Diagnostic Reagent Production: Used as a coating antigen or standard in ELISA and other immunoassays for the detection of PRV-specific antibodies.
• Structural Virology Studies: Essential for in vitro assembly studies, cryo-EM analysis, and understanding capsid formation and stability.
• Antiviral Drug Screening: Target protein for high-throughput screening assays to identify compounds that inhibit viral capsid assembly or protein-protein interactions.
• Immunology Research: Tool for investigating T-cell and B-cell epitope mapping and host immune responses to herpesvirus infections.
• Reference Standard: Serves as a purified protein standard for quality control in biomanufacturing and assay calibration.

Basic Information

Product Name	Major Capsid Protein, 142 Kda, Pseudorabies Virus
CAS No.	140879-07-8
Molecular Formula	Contact for details
Molecular Weight	~142 kDa
Synonyms	PRV Major Capsid Protein; Pseudorabies Virus VP5; Herpesvirus Suis 1 Major Capsid Protein; UL19 Protein (Pseudorabies Virus); 142 kDa Capsid Protein; PRV UL19 Gene Product; Aujeszky's Disease Virus Major Capsid Protein; Recombinant PRV Capsid Protein
EINECS	Contact for details

Quality Control

Our Major Capsid Protein is produced under stringent conditions to ensure high purity, biological activity, and batch-to-batch consistency. Each lot is rigorously tested using a suite of analytical techniques including SDS-PAGE, Western Blot, HPLC, and endotoxin assays. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional activity is provided with every shipment, supporting compliance with research and pre-clinical development standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein aliquots should be stored at -70°C to -80°C and avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or desiccant after use.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE & Western Blot)	Consistent with ~142 kDa protein; positive reactivity with specific antisera
Purity (SDS-PAGE, reducing conditions)	≥ 90%
Purity (HPLC)	≥ 95%
Protein Content (BCA/Bradford)	≥ 1.0 mg/vial
Endotoxin Level (LAL assay)	< 1.0 EU/µg
Biological Activity (ELISA binding)	Contact for details
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.