Description

(R)-n-Boc-3-Aminomethylpiperidine is a high-purity, chiral piperidine derivative used as a critical building block in advanced organic synthesis. This compound is essential for introducing a protected amino-methyl-piperidine moiety with specific stereochemistry into complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for neurological and psychiatric disorders.
• Peptidomimetics & Bioactive Molecule Synthesis: Used to construct constrained peptide analogs and other bioactive compounds that mimic natural peptide structures.
• Ligand & Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and receptor interactions in biological systems.
• Agrochemical Research: Employed in the discovery of new agrochemicals where specific chirality is required for biological activity.

Basic Information

Product Name	(R)-n-Boc-3-Aminomethylpiperidine
CAS No.	140645-23-4
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	(R)-1-Boc-3-(Aminomethyl)piperidine; (R)-3-(Aminomethyl)-1-N-Boc-piperidine; (R)-tert-Butyl 3-(aminomethyl)piperidine-1-carboxylate; (R)-N-Boc-3-piperidinemethanamine; (R)-1-(tert-Butoxycarbonyl)-3-(aminomethyl)piperidine; (R)-Boc-3-Amp; (R)-Boc-3-Aminomethylpiperidine; (3R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]piperidine-3-methanamine
EINECS	Contact for details

Quality Control

Our (R)-n-Boc-3-Aminomethylpiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee reproducible performance in your sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.