Description

Cyclohexanecarbonyl Fluoride, 1-(Trifluoromethyl)- (9Ci) is a specialized fluorinated building block of significant interest in advanced organic synthesis. This compound matters for its unique structural motif, combining a cyclohexane ring with both carbonyl fluoride and trifluoromethyl functionalities, enabling precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals. Its specific CAS number is 140451-78-1.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly those requiring fluorinated scaffolds to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of fluorine atoms can enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a building block for synthesizing fluorinated polymers or liquid crystals with unique thermal and chemical resistance properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for introducing the cyclohexanecarbonyl fluoride group into complex molecules via nucleophilic acyl substitution reactions.
• Fluorine Chemistry Research: A valuable compound for studying the reactivity and applications of acyl fluorides in synthetic methodology development.

Basic Information

Product Name	Cyclohexanecarbonyl Fluoride, 1-(Trifluoromethyl)- (9Ci)
CAS No.	140451-78-1
Molecular Formula	C8H10F4O
Molecular Weight	198.16 g/mol
Synonyms	1-(Trifluoromethyl)cyclohexanecarbonyl Fluoride; (1-(Trifluoromethyl)cyclohexyl)carbonyl Fluoride; Cyclohexanecarbonyl Fluoride, 1-(trifluoromethyl)-; 1-Trifluoromethyl-cyclohexanecarboxylic Acid Fluoride; α,α,α-Trifluorocyclohexaneacetyl Fluoride
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonyl Fluoride, 1-(Trifluoromethyl)- (9Ci) is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.