Description

Boc-n-Methylglycine N,o-Dimethylhydroxamide is a protected amino acid derivative, specifically a glycine analog with orthogonal protecting groups. This compound is a crucial building block in modern organic synthesis, particularly for the controlled introduction of modified glycine units into peptide chains and other complex molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide-based drugs and peptidomimetics, enabling the incorporation of N-methylated amino acids to enhance metabolic stability.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that utilize modified amino acid structures for targeted activity.
• Chemical Biology & Proteomics: Serves as a tool compound for studying enzyme mechanisms and for the site-specific modification of peptides and proteins.
• Combinatorial Chemistry: Employed in solid-phase and solution-phase peptide synthesis (SPPS) libraries for drug discovery screening.
• Material Science: Potential precursor for the synthesis of specialized polymers and dendrimers with tailored properties.

Basic Information

Product Name	Boc-n-Methylglycine N,o-Dimethylhydroxamide
CAS No.	140170-90-7
Molecular Formula	C10H20N2O4
Molecular Weight	232.28 g/mol
Synonyms	Boc-N-Me-Gly-ON(Me)OMe; (2-((tert-Butoxycarbonyl)(methyl)amino)acetic acid N-methoxy-N-methylamide; N-(tert-Butoxycarbonyl)-N-methylglycine N',O-dimethylhydroxamate; N-Boc-N-methylglycine N-methoxy-N-methylamide; N-(tert-Butoxycarbonyl)-N-methylglycine Weinreb amide; Boc-N-methylglycine Weinreb amide; N-Boc-sarcosine Weinreb amide
EINECS	Contact for details

Quality Control

Our Boc-n-Methylglycine N,o-Dimethylhydroxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.