Description

Mdr49 Protein, Drosophila is a highly purified recombinant protein derived from the fruit fly, *Drosophila melanogaster*, and is a critical research tool in molecular biology. This protein is essential for studying multidrug resistance mechanisms, cellular transport, and developmental biology pathways. It is primarily utilized by researchers and scientists in the biotechnology, pharmaceutical R&D, and academic sectors for proteomics, functional assays, and target validation.

Application

• Biomedical Research: Used as a key reagent in studies of P-glycoprotein homologs and multidrug resistance mechanisms in model organisms.
• Drug Discovery & Development: Serves as a target protein for screening and evaluating potential compounds that modulate efflux pump activity.
• Functional Proteomics: Employed in protein-protein interaction studies, pull-down assays, and western blotting to understand complex cellular networks.
• Enzyme & Binding Assays: Acts as a substrate or binding partner in kinetic studies and high-throughput screening (HTS) platforms.
• Academic & Institutional Research: Fundamental tool for graduate and postdoctoral research in genetics, cell biology, and developmental studies.
• Biomarker Development: Investigated for its role in cellular defense mechanisms, contributing to biomarker discovery for disease states.

Basic Information

Product Name	Mdr49 Protein, Drosophila
CAS No.	139947-59-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Drosophila Mdr49 Protein; Multidrug resistance protein 49; P-glycoprotein homolog Mdr49; CG5772-PA; MDR49; ATP-binding cassette sub-family B member 6; ABCB6 (Drosophila homolog); Recombinant Drosophila melanogaster Mdr49
EINECS	Contact for details

Quality Control

Our Mdr49 Protein, Drosophila is produced under stringent conditions to ensure high purity, stability, and biological activity. Each batch undergoes rigorous quality testing, including purity analysis by SDS-PAGE and HPLC, functional activity assays, and endotoxin level checks. A comprehensive Certificate of Analysis (COA) detailing identity, purity, concentration, and biological activity is provided with every shipment to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized protein at -20°C or below. Upon reconstitution, aliquot and store at -80°C to prevent repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the working environment is dry when handling.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Purity (SDS-PAGE)	≥ 90%
Identification (Western Blot)	Positive
Protein Concentration	≥ 0.5 mg/mL (after reconstitution)
Biological Activity	Assay-dependent; refer to COA
Endotoxin Level	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.