Description

Boc-α-Me-Dl-Val-Oh is a protected amino acid derivative, specifically a tert-butoxycarbonyl (Boc) protected form of α-methyl-DL-valine. This compound serves as a crucial chiral building block and intermediate in sophisticated organic synthesis, particularly in the pharmaceutical and peptide research sectors. Its primary value lies in enabling the controlled synthesis of complex molecules where stereochemistry and side-chain protection are critical. Key industries that utilize this intermediate include pharmaceutical R&D for novel active pharmaceutical ingredients (APIs), biotechnology for peptide mimetics, and academic research in medicinal chemistry.

Application

• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic peptides and peptidomimetics.
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• API Development: A key chiral synthon in the synthetic pathway of complex Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new drug candidates.
• Bioconjugation: Can be used to introduce valine-derived, protected functionalities into larger biomolecules.
• Chemical Biology Probes: Useful for synthesizing labeled or modified amino acids for biochemical studies.

Basic Information

Product Name	Boc-α-Me-Dl-Val-Oh
CAS No.	139938-00-4
Molecular Formula	C11H21NO4
Molecular Weight	231.29 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-α-methyl-DL-valine; Boc-α-Me-DL-Val-OH; 2-[(tert-Butoxycarbonyl)amino]-2-methyl-3-methylbutanoic acid; (RS)-2-[(tert-Butoxycarbonyl)amino]-2-methyl-3-methylbutyric acid; Boc-Amv-OH; DL-2-Amino-2-methyl-3-methylbutanoic acid N-Boc derivative; tert-Butyl (1-((RS)-1-carboxy-2-methylpropyl)-1-methyl)carbamate
EINECS	Contact for details

Quality Control

Our Boc-α-Me-Dl-Val-Oh is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with key parameters including assay (HPLC), chiral purity, and residual solvent content. Our quality commitment aligns with standards relevant for GMP-grade intermediates and research chemicals. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under dry conditions to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (typical ratio provided on COA)
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.