Description

4-Fluoro-3-Methylphenylboronic Acid is a high-purity organoboron compound, specifically a boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the efficient formation of carbon-carbon bonds via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce the valuable 4-fluoro-3-methylphenyl moiety into target structures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for molecules requiring the fluorinated aromatic scaffold.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular architecture is required.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and bioconjugates for studying biological systems and diagnostic applications.
• Custom Synthesis and Scale-up: Available for contract research organizations (CROs) and chemical development teams for process research and commercial-scale manufacturing projects.

Basic Information

Product Name	4-Fluoro-3-Methylphenylboronic Acid
CAS No.	139911-27-6
Molecular Formula	C7H8BFO2
Molecular Weight	153.95 g/mol
Synonyms	(4-Fluoro-3-methylphenyl)boronic acid; 3-Methyl-4-fluorophenylboronic acid; 4-Fluoro-m-tolylboronic acid; B-(4-Fluoro-3-methylphenyl)boronic acid; 4-Fluoro-3-methylbenzeneboronic acid; 139911-27-6; (4-Fluoro-3-methylphenyl)boronic acid, 95%
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.