Description

2',3'-Dideoxycytidine Monophosphate Diglyceride is a specialized nucleotide-lipid conjugate, representing a critical building block in advanced biochemical research and development. This compound is valued for its unique structure, which combines a modified nucleoside monophosphate with a diglyceride moiety, enabling specific interactions in lipid-based delivery systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on novel drug delivery platforms, prodrug development, and lipid nanoparticle formulation.

Application

• Lipid Nanoparticle (LNP) Formulation: A key functional component for constructing advanced delivery systems for nucleic acid therapeutics (e.g., mRNA, siRNA).
• Prodrug Synthesis: Serves as a precursor or intermediate in the design of lipophilic prodrugs to enhance cellular uptake and bioavailability of nucleoside analogs.
• Bioconjugation & Chemical Biology: Used as a tool compound for studying membrane interactions and creating labeled probes for cellular trafficking studies.
• Pharmaceutical Research: Employed in R&D for developing targeted therapies, especially in oncology and antiviral applications.
• Biomaterial Functionalization: Can be incorporated into biomaterials to impart specific nucleotide-based signaling or recognition properties.

Basic Information

Product Name	2',3'-Dideoxycytidine Monophosphate Diglyceride
CAS No.	139903-71-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ddCMP Diglyceride; 2',3'-Dideoxycytidine 5'-Monophosphate Diglyceride; Cytidine, 2',3'-dideoxy-, 5'-(dihydrogen phosphate), 1,2-diacyl-sn-glycerol ester; Nucleotide-lipid conjugate; Lipid-modified ddCMP; 1,2-Diacylglyceryl-2',3'-dideoxycytidine monophosphate
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxycytidine Monophosphate Diglyceride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including purity assessment by HPLC and structural confirmation by NMR and mass spectrometry, to ensure identity, strength, and composition. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.