Description

Sis1 Protein CAS NO 139874-81-0 is a high-purity recombinant protein essential for advanced biochemical and biomedical research. This product is critical for studies involving mitochondrial dynamics, membrane fusion, and cellular energy metabolism. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in proteomics, structural biology, and drug discovery.

Application

• Biochemical Research: Used as a key reagent in in vitro assays to study mitochondrial fusion and fission mechanisms.
• Drug Discovery & Screening: Serves as a target protein in high-throughput screening platforms for identifying novel therapeutics targeting mitochondrial dysfunction.
• Proteomics & Structural Biology: Essential for protein-protein interaction studies, crystallization trials, and determining three-dimensional protein structures.
• Antibody Production & Development: Acts as a high-quality immunogen for generating specific monoclonal and polyclonal antibodies.
• Cell Biology Studies: Employed in cellular transfection experiments to investigate the role of Sis1 in cellular stress responses and apoptosis.
• Diagnostic Assay Development: Used as a reference standard in the development of ELISA and other immunoassays for research purposes.

Basic Information

Product Name	Sis1 Protein
CAS No.	139874-81-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sis1; SIS1 Protein; Mitochondrial Fission 1 Protein; Recombinant Sis1 Protein; FIS1_HUMAN; Tetratricopeptide repeat protein 11; TTC11; hFis1; hFIS1 Protein
EINECS	Contact for details

Quality Control

Our Sis1 Protein is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation by mass spectrometry, and functional activity assays. A detailed Certificate of Analysis (COA) documenting purity, concentration, endotoxin levels, and biological activity is provided with every shipment to support your research compliance and reproducibility requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Purity (SDS-PAGE)	≥ 95%
Identification (Mass Spec)	Conforms
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Assessed by functional assay
Protein Concentration	≥ 90% of label claim
Solubility	Clear, colorless solution in specified buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.