Description

Rad9 Protein is a critical checkpoint protein involved in the cellular DNA damage response and repair pathways. This high-purity recombinant protein is essential for advanced life science research, enabling the study of cell cycle regulation, genomic stability, and cancer biology. It is a vital reagent for pharmaceutical R&D, academic institutions, and diagnostic developers focusing on oncology and DNA repair mechanisms.

Application

• Biochemical Research: Used as a key substrate or binding partner in in vitro assays to study DNA damage signaling cascades.
• Drug Discovery & Screening: Employed in high-throughput screening platforms to identify novel inhibitors or modulators of the DNA damage response for cancer therapeutics.
• Antibody Production & Validation: Serves as a high-quality immunogen for generating specific monoclonal or polyclonal antibodies.
• Diagnostic Development: Utilized as a reference standard in ELISA or other immunoassays to detect Rad9 expression or autoantibodies in clinical samples.
• Protein-Protein Interaction Studies: Essential for pull-down assays, co-immunoprecipitation, and surface plasmon resonance (SPR) to map interaction networks with partners like Hus1, Rad1, and other checkpoint proteins.
• Enzymatic Activity Assays: Used to investigate its role in cell cycle checkpoint activation and apoptosis regulation.

Basic Information

Product Name	Rad9 Protein
CAS No.	139691-42-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Rad9; hRad9; RAD9 Homolog A; RAD9A; DNA Repair Protein RAD9 Homolog A; Checkpoint Protein Rad9; Cell Cycle Checkpoint Protein RAD9
EINECS	Contact for details

Quality Control

Our Rad9 Protein is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation by mass spectrometry, and functional activity validation in relevant biochemical assays. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at ≤ -20°C. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	Lyophilized powder or clear solution
Purity (SDS-PAGE)	≥ 90%
Identification (Mass Spec)	Conforms
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Assay-dependent; specified per lot
Protein Concentration	Specified per lot
Buffer Composition	Specified per lot

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.