Description

2-Deoxy-2-((3R)-3-Hydroxy-Tetradecanamido)-3-o-(3-Hydroxytetradecanyl)-4-o-Phosphonoglucopyranose is a sophisticated synthetic glycolipid derivative, representing a key intermediate in advanced biochemical research and pharmaceutical development. This compound is valued for its structural similarity to bacterial lipid A components, making it a critical tool for studying innate immune system activation and inflammation pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in immunology, vaccine adjuvant development, and novel therapeutic agent synthesis.

Application

• Immunological Research: Serves as a reference standard and synthetic analog for studying Toll-like receptor 4 (TLR4) signaling and macrophage activation.
• Vaccine Adjuvant Development: Investigated as a potential synthetic component for next-generation vaccine formulations to enhance immunogenicity.
• Pharmaceutical Intermediate: Used in the synthesis of more complex immunomodulators and targeted therapeutic agents.
• Biochemical Tool Compound: Employed in assay development and as a molecular probe to elucidate lipid-mediated cell signaling mechanisms.
• Academic Research: Supports fundamental studies in glycobiology, lipid biochemistry, and host-pathogen interactions.

Basic Information

Product Name	2-Deoxy-2-((3R)-3-Hydroxy-Tetradecanamido)-3-o-(3-Hydroxytetradecanyl)-4-o-Phosphonoglucopyranose
CAS No.	139623-12-4
Molecular Formula	C40H78NO13P
Molecular Weight	812.02 g/mol
Synonyms	Monophosphoryl Lipid A (MPLA) synthetic analog; 2-Deoxy-2-[(3R)-3-hydroxytetradecanamido]-3-O-[(3R)-3-hydroxytetradecyl]-α-D-glucopyranose 4-(dihydrogen phosphate); Synthetic Lipid A derivative; TLR4 agonist intermediate; Phosphonoglucopyranose lipid; Glucosamine-based phospholipid; Glycolipid A mimetic
EINECS	Contact for details

Quality Control

Our production of this high-purity biochemical adheres to stringent quality protocols. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring traceability and consistency for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.