Description

1-Iodo-1-(Trifluoromethoxy)Tetrafluoroethane is a specialized fluorinated organic compound featuring a unique combination of iodine and trifluoromethoxy functional groups. This structure makes it a valuable intermediate and reagent for introducing fluorinated motifs in advanced chemical synthesis. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical and agrochemical sectors for building complex molecules. Its properties are also leveraged in the development of specialty materials and electronic chemicals.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated segments for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and iodine atoms contribute to biological activity and environmental persistence.
• Organic Synthesis Reagent: Serves as a versatile reagent for introducing the -OCF3 group and iodine atom in cross-coupling reactions and nucleophilic substitutions.
• Liquid Crystal & Electronic Chemicals: A potential precursor in the manufacture of fluorinated liquid crystals and dielectric fluids for the electronics industry.
• Specialty Polymer Modification: Employed to incorporate fluorine into polymer backbones, aiming to improve chemical resistance, thermal stability, and surface properties.
• Research & Development: A critical compound for academic and industrial R&D focused on organofluorine chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	1-Iodo-1-(Trifluoromethoxy)Tetrafluoroethane
CAS No.	139604-89-0
Molecular Formula	C3F7IO
Molecular Weight	335.93 g/mol
Synonyms	1,1,1,2-Tetrafluoro-2-iodo-2-(trifluoromethoxy)ethane; 2-Iodo-1,1,1,2-tetrafluoro-2-(trifluoromethoxy)ethane; Iodotrifluoromethoxytetrafluoroethane; FC-227-7-I; HFE-227-7-I; Perfluoro(iodomethyl methyl ether); R-227-7-I
EINECS	Contact for details

Quality Control

Every batch of 1-Iodo-1-(Trifluoromethoxy)Tetrafluoroethane is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by GC, HPLC, NMR, and FTIR. Our quality system ensures traceability and consistency, supporting your cGMP and ISO-compliant manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. For long-term storage, maintaining the container under an inert atmosphere (e.g., nitrogen or argon) is recommended to preserve stability. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.5%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~2.1 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.