Description

N'-Aminooxymethylcarbonylhydrazino-D-Biotin is a high-purity, advanced biotin derivative designed for sophisticated bioconjugation and labeling applications. This compound serves as a critical linker molecule, enabling the precise attachment of biotin tags to proteins, antibodies, and other biomolecules for detection and purification. It is essential for researchers and manufacturers in the fields of pharmaceutical development, diagnostic assay production, and advanced life science research who require reliable, high-quality intermediates for creating sensitive detection systems.

Application

• Bioconjugation Reagent: Used as a specialized linker for attaching biotin to antibodies, proteins, and peptides in immunoassay and diagnostic kit development.
• Affinity Chromatography Ligand Synthesis: A key intermediate in the production of biotinylated ligands for streptavidin/avidin-based purification columns.
• Molecular Probes and Diagnostics: Integral in the synthesis of fluorescent or enzyme-linked biotin probes for in vitro diagnostics (IVD) and histochemistry.
• Drug Delivery Systems: Employed in research for creating biotin-targeted drug conjugates and nanoparticle formulations.
• Biochemical Research: Utilized in studying protein-protein interactions, cellular trafficking, and other molecular biology techniques reliant on the strong biotin-streptavidin interaction.
• Surface Functionalization: Used to biotinylate surfaces for biosensor development and microarray platforms.

Basic Information

Product Name	N'-Aminooxymethylcarbonylhydrazino-D-Biotin
CAS No.	139585-03-8
Molecular Formula	C12H21N5O4S
Molecular Weight	331.39 g/mol
Synonyms	Biotin-XX hydrazide; D-Biotinyl-6-aminocaproic acid hydrazide; Biotin LC hydrazide; (+)-Biotin-6-amidocaproic hydrazide; Biotinamidocaproyl hydrazide; 6-((6-((5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl)amino)hexanoyl)hydrazinecarboxamido)methanol; Biotin long-chain hydrazide
EINECS	Contact for details

Quality Control

Our N'-Aminooxymethylcarbonylhydrazino-D-Biotin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.