Description

Connective Tissue Growth Factor (CTGF) is a cysteine-rich matricellular protein that plays a pivotal role in cell adhesion, migration, proliferation, and extracellular matrix synthesis. This key signaling molecule is essential for research into fibrotic diseases, wound healing, and tissue regeneration processes. It is a critical reagent for pharmaceutical R&D, biotechnology, and academic research focused on connective tissue disorders, oncology, and cardiovascular biology.

Application

• Biomedical Research: Fundamental studies on fibrosis mechanisms in liver, lung, kidney, and skin.
• Drug Discovery & Development: Target validation and screening for anti-fibrotic and anti-angiogenic therapeutics.
• Cell Culture & Tissue Engineering: Used as a growth supplement to study chondrocyte, osteoblast, and fibroblast behavior in vitro.
• Wound Healing Studies: Investigation of its role in scar formation and tissue repair pathways.
• Oncology Research: Exploring its function in tumor stroma formation, metastasis, and angiogenesis.
• Diagnostic Assay Development: Production of calibration standards and controls for CTGF detection kits (ELISA).

Basic Information

Product Name	Connective Tissue Growth Factor
CAS No.	139568-91-5
Molecular Formula	C19H29N5O8S
Molecular Weight	487.5 g/mol
Synonyms	CTGF; CCN2; IGFBP8; HCS24; FISP12; Connective tissue growth factor; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; Fibroblast-inducible secreted protein 12; CCN family member 2
EINECS	Contact for details

Quality Control

Our Connective Tissue Growth Factor is produced and tested under stringent conditions. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and biological activity. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity by HPLC, endotoxin levels, and bioactivity assay results. Our quality system supports research requiring high-grade, consistent biological reagents.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Aliquot upon receipt for optimal preservation of activity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity	Determined by cell proliferation assay
Endotoxin Level	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.