Description

(5S)-5-1-Methylethyl-2-Pyrrolidinone is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a valuable building block for the development of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating active ingredients with specific biological activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug research.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for stereoselective chemical transformations.
• Agrochemical Synthesis: Serves as a building block for creating chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is critical.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(5S)-5-1-Methylethyl-2-Pyrrolidinone
CAS No.	139564-41-3
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	(S)-5-Isopropyl-2-pyrrolidinone; (S)-(-)-5-Isopropyl-2-pyrrolidinone; L-5-Isopropyl-2-pyrrolidinone; (5S)-5-Isopropylpyrrolidin-2-one; (S)-5-(1-Methylethyl)-2-pyrrolidinone; (S)-5-Isopropyl-2-pyrrolidone
EINECS	Contact for details

Quality Control

Our (5S)-5-1-Methylethyl-2-Pyrrolidinone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.