Description

T-Butyloxycarbonyl-Cyclo(Cysteinyl-T-Butylseryl-Asparaginyl-Leucyl-T-Butylseryl-T-Butylthreonyl-Cysteinyl)-Valyl-Leucyl-Glycine is a complex, synthetic cyclic peptide derivative featuring Boc (tert-butyloxycarbonyl) and multiple t-butyl-protected amino acid residues, designed for advanced research and development. This compound is of significant interest for its role as a key intermediate or reference standard in the synthesis of novel peptide-based pharmaceuticals and biochemical probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, drug discovery, and the development of therapeutic agents targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex peptide drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, receptor-ligand binding assays, and structure-activity relationship (SAR) investigations.
• Peptide Library Synthesis: A valuable component for constructing focused libraries in combinatorial chemistry for high-throughput screening against biological targets.
• Protease Inhibitor Development: The cyclic and protected structure makes it a candidate scaffold for designing and testing novel protease inhibitors.
• Academic Research: Employed in university and institutional labs for methodological development in peptide coupling, deprotection strategies, and conformational analysis.

Basic Information

Product Name	T-Butyloxycarbonyl-Cyclo(Cysteinyl-T-Butylseryl-Asparaginyl-Leucyl-T-Butylseryl-T-Butylthreonyl-Cysteinyl)-Valyl-Leucyl-Glycine
CAS No.	139555-60-5
Molecular Formula	C58H98N12O19S2
Molecular Weight	1331.6 g/mol
Synonyms	Boc-Cys(tBu)-Ser(tBu)-Asn-Leu-Ser(tBu)-Thr(tBu)-Cys(tBu)-Val-Leu-Gly-OH (cyclic 1→8 disulfide); Cyclo(Boc-Cys(tBu)-Ser(tBu)-Asn-Leu-Ser(tBu)-Thr(tBu)-Cys(tBu))-Val-Leu-Gly; Boc-Cyclic(Cys(tBu)-Ser(tBu)-Asn-Leu-Ser(tBu)-Thr(tBu)-Cys(tBu))-Val-Leu-Glycine; Protected Cyclic Peptide 139555-60-5; Cyclic Boc-Peptide Intermediate; CAS 139555-60-5
EINECS	Contact for details

Quality Control

Our T-Butyloxycarbonyl-Cyclo(Cysteinyl-T-Butylseryl-Asparaginyl-Leucyl-T-Butylseryl-T-Butylthreonyl-Cysteinyl)-Valyl-Leucyl-Glycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis where applicable, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.