Description

Tyr-C-Peptide Human CAS NO 139532-11-9 is a synthetic peptide fragment corresponding to the C-terminal region of human tyrosinase, a key enzyme in melanin biosynthesis. This high-purity reference standard is critical for biochemical research, enabling precise study of enzyme function, antigen-antibody interactions, and melanogenesis pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and diagnostic sectors for applications in immunology, oncology, and pigment disorder research.

Application

• Biochemical Research: Used as a reference standard and substrate analog in enzymatic studies of tyrosinase activity and melanin production.
• Immunoassay Development: Serves as a critical antigen for the production and characterization of monoclonal and polyclonal antibodies targeting human tyrosinase.
• Cancer Research: Employed in melanoma research to investigate tumor-associated antigens and develop potential immunotherapeutic and diagnostic strategies.
• Diagnostic Reagent Manufacturing: Incorporated as a key component in ELISA kits and other in-vitro diagnostic (IVD) assays for detecting tyrosinase-related antibodies.
• Peptide Synthesis & Drug Discovery: Acts as a building block or a lead compound for the design and synthesis of novel inhibitors targeting melanogenesis for cosmetic or therapeutic purposes.
• Quality Control: Functions as a system suitability standard in analytical laboratories for method validation and quality control of related biopharmaceutical products.

Basic Information

Product Name	Tyr-C-Peptide Human
CAS No.	139532-11-9
Molecular Formula	C41H62N12O12S
Molecular Weight	923.06 g/mol
Synonyms	Tyrosinase C-Terminal Peptide (Human); TYR Peptide (469-477); Melanoma Antigen Peptide; HLA-A*0201-restricted Tyrosinase Peptide; YMDGTMSQV; Tyr (369-377); Tyr369-377; gp75369-377
EINECS	Contact for details

Quality Control

Our Tyr-C-Peptide Human is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, Mass Spectrometry (MS) for identity confirmation, and Amino Acid Analysis (AAA). Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research-grade standards and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.