Description

1-(2-Fluorobenzoyl)Piperazine is a high-purity fluorinated piperazine derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with enhanced biological activity and specific physicochemical properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom can improve metabolic stability and bioavailability.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced organic materials requiring fluorinated aromatic components.

Basic Information

Product Name	1-(2-Fluorobenzoyl)Piperazine
CAS No.	139516-64-6
Molecular Formula	C11H13FN2O
Molecular Weight	208.23 g/mol
Synonyms	2-Fluorobenzoylpiperazine; 1-(2-Fluorobenzoyl)piperazine; N-(2-Fluorobenzoyl)piperazine; Piperazine, 1-(2-fluorobenzoyl)-; 2-Fluorophenyl(piperazin-1-yl)methanone; o-Fluorobenzoylpiperazine; 139516-64-6; Fluorobenzoyl piperazine
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorobenzoyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.