Description

Vasopressin, 1-(β-Mercapto-Beta,β-Cyclopentamethylene Propionic Acid)-(o-Ethyl)Tyr(2)-Val(4)-Lys(8)-N(6)-Carboxytetramethylrhodamine- CAS NO 139468-40-9 is a chemically modified, fluorescently labeled analog of the neurohypophysial hormone vasopressin. This specialized compound is engineered for advanced research applications, offering a powerful tool for the visualization and study of vasopressin receptor interactions and cellular pathways. It is primarily utilized by pharmaceutical researchers, academic biochemists, and diagnostic developers working in neuroendocrinology, receptor pharmacology, and high-content screening.

Application

• Receptor Binding and Localization Studies: Used as a high-affinity fluorescent tracer for visualizing vasopressin V1a and V2 receptor distribution in cell cultures and tissue sections.
• High-Throughput Screening (HTS): Serves as a key reagent in fluorescence-based assays for identifying and characterizing novel vasopressin receptor agonists or antagonists.
• Cellular Imaging and Microscopy: Enables real-time, live-cell imaging of receptor internalization, trafficking, and downstream signaling events.
• Biophysical Research: Employed in Fluorescence Resonance Energy Transfer (FRET) or Fluorescence Polarization (FP) assays to study protein-protein interactions and conformational changes.
• Diagnostic Probe Development: Acts as a precursor or model compound for developing targeted imaging probes for research in conditions related to vasopressin dysregulation.

Basic Information

Product Name	Vasopressin, 1-(β-Mercapto-Beta,β-Cyclopentamethylene Propionic Acid)-(o-Ethyl)Tyr(2)-Val(4)-Lys(8)-N(6)-Carboxytetramethylrhodamine- CAS NO 139468-40-9
CAS No.	139468-40-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	[d(CH2)5¹, Tyr(Me)², Val⁴, Lys⁸(N-ε-TAMRA)]-Vasopressin; TAMRA-Lys-Vasopressin analog; Fluorescent Vasopressin V1a antagonist; 1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid)-2-(O-methyl)tyrosine-4-valine-8-lysine(N-ε-carboxytetramethylrhodamine)-vasopressin; Arg⁸-Vasopressin, TAMRA-labeled analog; AVP-TAMRA conjugate; Vasopressin-TAMRA
EINECS	Contact for details

Quality Control

This high-purity biochemical is manufactured under controlled conditions and undergoes rigorous analytical characterization to ensure identity, purity, and performance consistency. Quality is verified by techniques including HPLC, mass spectrometry (MS), and absorbance/fluorescence spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, fluorescence properties, and functional activity data is provided with each batch to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into single-use quantities to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Red to dark red solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Absorption Max (λmax)	~554 nm
Emission Max	~576 nm
Extinction Coefficient (ε)	~90,000 cm⁻¹M⁻¹
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.