Description

(S)-(+)-4-Methoxy-Mandelonitrile is a high-purity chiral building block and synthetic intermediate of significant commercial importance. Its enantiomerically pure structure makes it a critical precursor in the synthesis of complex pharmaceutical actives and fine chemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemistry is required for efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of enantiomerically pure drugs, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the manufacture of advanced, optically active pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a standard substrate or ligand precursor in the development of new chiral catalysts and methodologies.
• Fine Chemical Production: Building block for fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & R&D: Utilized in university and corporate laboratories for synthetic organic chemistry research and process development.

Basic Information

Product Name	(S)-(+)-4-Methoxy-Mandelonitrile
CAS No.	139406-83-0
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	(S)-(+)-4-Methoxybenzaldehyde cyanohydrin; (S)-4-Methoxy-mandelonitrile; (S)-α-Hydroxy-4-methoxybenzeneacetonitrile; (S)-O-Methylmandelonitrile; (S)-2-Hydroxy-2-(4-methoxyphenyl)acetonitrile; (S)-4-Methoxybenzaldehyde cyanohydrin; (S)-p-Methoxymandelonitrile
EINECS	Contact for details

Quality Control

Our (S)-(+)-4-Methoxy-Mandelonitrile is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.