Description

4-Trifluoromethoxyphenylboronic Acid is a high-value organoboron building block characterized by its trifluoromethoxy-substituted aromatic ring. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for forming carbon-carbon bonds. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors to introduce the versatile 4-(trifluoromethoxy)phenyl moiety into complex target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the metabolically stable and lipophilic trifluoromethoxy group.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of advanced electronic materials for displays and lighting applications.
• Polymer Chemistry: Employed to incorporate functional aromatic units into specialty polymers, modifying their thermal and chemical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new chemical entities and catalytic processes.
• Ligand Synthesis: Used to prepare sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Trifluoromethoxyphenylboronic Acid
CAS No.	139301-27-2
Molecular Formula	C7H6BF3O3
Molecular Weight	205.93 g/mol
Synonyms	(4-(Trifluoromethoxy)phenyl)boronic Acid; 4-(Trifluoromethoxy)benzeneboronic Acid; p-(Trifluoromethoxy)phenylboronic Acid; B-[4-(Trifluoromethoxy)phenyl]boronic Acid; 4-Trifluoromethoxybenzeneboronic Acid; 4-CF3O-C6H4-B(OH)2; 1-Borono-4-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 4-Trifluoromethoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring material traceability and compliance with cGMP and ISO standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical: 98-99%)
Water Content (KF)	≤1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.