Description

(S)-H8-Binap is a high-performance, hydrogenated derivative of the renowned BINAP ligand, specifically designed for enhanced stability and catalytic efficiency. This compound is a critical chiral ligand in asymmetric synthesis, enabling the production of enantiomerically pure intermediates for advanced pharmaceuticals and fine chemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-selectivity catalysts for challenging transformations.

Application

• As a chiral ligand for asymmetric hydrogenation reactions in pharmaceutical API synthesis.
• Catalyst for enantioselective C-C bond formation, such as in Suzuki-Miyaura cross-couplings.
• Key component in the synthesis of chiral amines, alcohols, and other valuable building blocks.
• Use in process chemistry for the scale-up of enantiopure drug candidates.
• Research and development of novel catalytic systems in academic and industrial laboratories.
• Production of specialty flavors, fragrances, and advanced materials requiring high optical purity.

Basic Information

Product Name	(S)-H8-Binap
CAS No.	139139-93-8
Molecular Formula	C44H32P2
Molecular Weight	622.67 g/mol
Synonyms	(S)-(-)-2,2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; (S)-H8-BINAP; (S)-Octahydrobinap; (S)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-binaphthyl-2,2'-diyl)bis(diphenylphosphine); H8-BINAP-(S); (S)-H8BINAP
EINECS	Contact for details

Quality Control

Our (S)-H8-Binap is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and elemental analysis, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). Due to its sensitivity to oxidation, the container should only be opened in an inert environment and resealed immediately after use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.