Description

(R)-H8-Binap CAS NO 139139-86-9 is a high-value, chiral hydrogenated derivative of the renowned BINAP ligand, prized for its exceptional stereoselectivity in asymmetric catalysis. This ligand is critical for enabling highly efficient and enantioselective transformations, particularly in the synthesis of complex pharmaceutical intermediates and fine chemicals. It is an essential tool for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require robust and reliable chiral induction.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the production of enantiomerically pure amino acids and pharmaceutical intermediates.
• Catalyst component in asymmetric C-C bond-forming reactions, such as Suzuki-Miyaura cross-couplings and Heck reactions.
• Key reagent for the enantioselective synthesis of natural products and bioactive molecules in academic and industrial R&D.
• Used in the development of novel catalytic systems for the agrochemical industry to create chiral active ingredients.
• Facilitates asymmetric isomerization and cyclization reactions in fine chemical manufacturing.
• Employed in methodological studies to explore new avenues in transition metal catalysis and ligand design.

Basic Information

Product Name	(R)-H8-Binap
CAS No.	139139-86-9
Molecular Formula	C44H32P2
Molecular Weight	622.67 g/mol
Synonyms	(R)-(-)-H8-BINAP; (R)-2,2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; (R)-H8-1,1'-Binaphthyl-2,2'-diyl)bis(diphenylphosphine); (R)-Octahydro-1,1'-binaphthyl-2,2'-diylbis(diphenylphosphine); (R)-H8-BINAP ligand; (R)-H8BINAP
EINECS	Contact for details

Quality Control

Our (R)-H8-Binap is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding catalytic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and key impurity profiles. We adhere to cGMP standards where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain catalytic activity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.