Description

Histidine-Rich Calcium-Binding Protein is a specialized protein characterized by its high affinity for calcium ions, primarily due to its unique histidine-rich sequence. This compound is crucial for researchers and developers in life sciences, serving as a key biochemical tool for studying calcium signaling pathways and protein-metal interactions. It is essential for professionals in pharmaceutical R&D, diagnostic assay development, and advanced biochemical research requiring high-purity, functionally active proteins.

Application

• Biochemical Research: Used as a model protein for studying calcium ion (Ca²⁺) binding kinetics, protein conformation changes, and metal-protein interactions in vitro.
• Diagnostic Development: Serves as a critical component or calibration standard in the development of immunoassays and biosensors for calcium-related metabolic disorders.
• Pharmaceutical R&D: Employed in drug discovery programs targeting calcium-mediated cellular processes, including as a target for validating novel therapeutic compounds.
• Cell Signaling Studies: Utilized to modulate intracellular calcium levels and investigate downstream signaling cascades in cellular and molecular biology.
• Reference Standard: Acts as a high-purity reference material in quality control laboratories for protein analysis and characterization.
• Nutraceutical Research: Investigated for potential applications in formulations aimed at supporting bone health and mineral metabolism.

Basic Information

Product Name	Histidine-Rich Calcium-Binding Protein
CAS No.	139135-52-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HRCBP; Histidine-Rich Ca²⁺-Binding Protein; Calcium-Binding Protein, Histidine-Rich; CAS 139135-52-7
EINECS	Contact for details

Quality Control

Our Histidine-Rich Calcium-Binding Protein is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and functional activity, meeting the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), biological activity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Biological Activity	Contact for details
Endotoxin Level (LAL)	< 1.0 EU/mg
Moisture Content (KF)	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.