Description

2-Chloro-N-(2,2,2-trifluoroethyl)propanamide is a specialized organofluorine compound that serves as a valuable synthetic intermediate. Its molecular structure, featuring both chloro and trifluoroethyl groups, makes it a key building block for introducing specific functionalities into target molecules. This compound is primarily utilized in advanced research and development within the pharmaceutical and agrochemical sectors. It is essential for chemists developing novel active ingredients that require precise fluorinated architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoroethyl moiety can enhance biological activity and environmental persistence profiles.
• Fluorinated Building Block: Employed in organic synthesis to incorporate the -CH2CF3 group into complex molecules for material science and specialty chemical applications.
• Chemical Research & Development: Serves as a standard reagent in academic and industrial R&D labs for methodology development and exploring new fluorination pathways.
• Ligand and Catalyst Preparation: Can be used in the synthesis of specialized ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2-Chloro-N-(2,2,2-trifluoroethyl)propanamide
CAS No.	139126-57-1
Molecular Formula	C5H7ClF3NO
Molecular Weight	189.56 g/mol
Synonyms	2-Chloro-N-(2,2,2-trifluoroethyl)propanamide; Propanamide, 2-chloro-N-(2,2,2-trifluoroethyl)-; 2-Chloro-N-(trifluoroethyl)propionamide; α-Chloro-N-(2,2,2-trifluoroethyl)propionamide; 139126-57-1; N-(2,2,2-Trifluoroethyl)-2-chloropropanamide
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-N-(2,2,2-trifluoroethyl)propanamide is produced and tested under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.