Description

Proline-Rich Structural Protein, Brugia is a specialized biochemical reagent derived from parasitic nematodes of the *Brugia* genus. This protein is of significant interest in parasitology and tropical disease research due to its unique structural composition and role in host-pathogen interactions. It serves as a critical research tool for scientists and institutions focused on developing diagnostics, vaccines, and therapeutic strategies for lymphatic filariasis and related neglected tropical diseases.

Application

• Biomedical Research: Fundamental studies on the molecular biology, immunology, and biochemistry of filarial parasites.
• Diagnostic Development: Used as a target antigen or reference standard in the development and validation of immunoassays (e.g., ELISA) for detecting *Brugia* infections.
• Vaccine Research: Investigated as a potential vaccine candidate to elicit protective immune responses against lymphatic filariasis.
• Drug Discovery: Employed in screening platforms and target validation studies for novel anti-filarial compounds.
• Immunological Studies: Analysis of host immune responses, including antibody profiling and T-cell epitope mapping.
• Comparative Proteomics: Serves as a reference protein in comparative studies of structural proteins across different nematode species.

Basic Information

Product Name	Proline-Rich Structural Protein, Brugia
CAS No.	139075-02-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Brugia Proline-Rich Protein; Brugia Structural Protein; Filarial Proline-Rich Protein; Brugia malayi Proline-Rich Antigen; BmPRP; Brugia timori Proline-Rich Protein; Lymphatic Filariasis Research Protein; Nematode Cuticular Protein
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and suitability for sensitive research applications. Quality assurance includes identity confirmation via spectroscopic methods and purity assessment. A comprehensive Certificate of Analysis (COA) detailing specific parameters such as purity, biological activity (where applicable), and absence of key contaminants is provided with each shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For extended storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to reference spectrum
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 95% of dry weight
Endotoxin Level (LAL)	< 1.0 EU/mg
Solubility	Soluble in appropriate aqueous buffers
Moisture Content (KF)	< 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.