Description

Core Ii Protein, Ubiquinol-Cytochrome C Reductase is a highly purified mitochondrial membrane protein complex, also known as Complex III, which plays a critical role in the electron transport chain. This essential biochemical reagent is vital for research into cellular respiration, energy metabolism, and mitochondrial dysfunction. It is primarily utilized by researchers and manufacturers in the fields of biochemistry, molecular biology, and pharmaceutical development for enzyme activity studies, assay development, and drug discovery targeting metabolic diseases.

Application

• Biochemical Research: Used as a key reagent for studying the mechanism of the mitochondrial electron transport chain and oxidative phosphorylation.
• Enzyme Activity Assays: Serves as a standard or active component in spectrophotometric assays to measure Complex III activity in cell lysates or isolated mitochondria.
• Drug Discovery & Screening: Employed in high-throughput screening platforms to identify and evaluate novel compounds that modulate mitochondrial function for therapeutic applications.
• Diagnostic Kit Development: Integrated into diagnostic kits for the assessment of mitochondrial disorders and metabolic deficiencies in clinical research settings.
• Educational & Reference Standard: Provides a purified protein standard for university teaching labs and quality control in related bioproduct manufacturing.

Basic Information

Product Name	Core Ii Protein, Ubiquinol-Cytochrome C Reductase
CAS No.	139047-31-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Complex III; Ubiquinol-Cytochrome-c Reductase; Cytochrome bc1 Complex; Mitochondrial Complex III; Coenzyme Q-Cytochrome c Reductase; Core 2 Protein; QCR; EC 1.10.2.2
EINECS	Contact for details

Quality Control

Our Core Ii Protein, Ubiquinol-Cytochrome C Reductase is produced under stringent conditions to ensure high biological activity and purity, suitable for sensitive research applications. Each batch is subjected to rigorous quality testing, including activity assays and purity analysis. A comprehensive Certificate of Analysis (COA) detailing specific results for purity, activity, and other critical parameters is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Purity (SDS-PAGE)	≥ 90%
Specific Activity	Contact for details
Protein Concentration	Contact for details
Buffer Composition	Contact for details
Identification (Activity)	Conforms
Endotoxin Level	< 1.0 EU/mg protein

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.