Description

Cyclopentanecarboxylic Acid, 1-[(2-Amino-1-Oxopropyl)Amino]-, (S)- (9Ci) is a high-purity, chiral organic compound featuring a cyclopentane backbone functionalized with a carboxylic acid and a peptide-like amide linkage. This specific stereochemistry and functional group arrangement make it a valuable non-natural amino acid derivative and a critical advanced pharmaceutical intermediate (API intermediate) for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic agents, including peptide-based drugs and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for peptide-mimetic drugs and protease inhibitors.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce constrained, non-proteinogenic amino acid residues that can enhance metabolic stability and binding affinity.
• Medicinal Chemistry Research: Serves as a versatile scaffold in drug discovery programs for creating focused libraries and optimizing lead compounds targeting various diseases.
• Bioconjugation: The carboxylic acid and amine functionalities allow for selective conjugation to other molecules, proteins, or solid supports for diagnostic or therapeutic applications.
• Chemical Biology Probes: Employed in the development of activity-based probes and inhibitors to study enzyme function and biological pathways.
• Asymmetric Synthesis Catalyst Ligand: The chiral structure can be utilized to derive ligands for metal catalysts used in enantioselective synthesis.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 1-[(2-Amino-1-Oxopropyl)Amino]-, (S)- (9Ci)
CAS No.	138999-55-0
Molecular Formula	C9H16N2O3
Molecular Weight	200.24 g/mol
Synonyms	(S)-1-[(2-Aminopropanoyl)amino]cyclopentane-1-carboxylic acid; L-Alanyl-1-aminocyclopentanecarboxylic acid; 1-(L-Alanylamino)cyclopentanecarboxylic acid; ACC; 1-Aminocyclopentanecarboxylic acid, N-alanyl-, (S)-; ACPC derivative; Non-natural amino acid derivative; CAS 138999-55-0
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 1-[(2-Amino-1-Oxopropyl)Amino]-, (S)- (9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.