Description

Major T Cell Antigen, Mycobacterium Leprae is a highly purified, immunologically active peptide antigen derived from the causative agent of leprosy. This compound is critical for immunological research and diagnostic development, specifically for studying T-cell-mediated immune responses to *Mycobacterium leprae* infection. It is an essential reagent for researchers and diagnostic manufacturers in the fields of infectious disease immunology, vaccine development, and autoimmune research, where precise antigenic stimulation is required.

Application

• Immunological Research: Used as a specific antigen to stimulate and study T-cell responses in vitro, aiding in the understanding of host-pathogen interactions in leprosy.
• Diagnostic Development: Serves as a key component in the development of advanced diagnostic assays, such as ELISPOT and interferon-gamma release assays (IGRAs), for detecting cellular immunity to *M. leprae*.
• Vaccine Research: Employed in preclinical studies to evaluate candidate vaccine efficacy by measuring antigen-specific T-cell activation and cytokine production.
• Autoimmune Disease Studies: Investigated for potential cross-reactivity in autoimmune conditions, helping to elucidate mechanisms of molecular mimicry.
• Biomarker Discovery: Utilized in proteomic and immunoproteomic studies to identify novel immune biomarkers associated with leprosy progression or resistance.
• Quality Control for Therapeutics: Acts as a reference standard in the quality control of immunotherapies and other biological products targeting mycobacterial diseases.

Basic Information

Product Name	Major T Cell Antigen, Mycobacterium Leprae
CAS No.	138988-32-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Mycobacterium leprae Antigen; Leprosy T-Cell Antigen; M. leprae Major T-Cell Epitope; Immunodominant Antigen of M. leprae; Leprosy Diagnostic Antigen; Mycobacterial Peptide Antigen; T-Cell Stimulatory Antigen (ML); Antigen ML
EINECS	Contact for details

Quality Control

Our Major T Cell Antigen, Mycobacterium Leprae is produced under stringent conditions to ensure batch-to-batch consistency and high immunological purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment, mass spectrometry for identity confirmation, and functional bioassays to verify T-cell stimulatory activity. A detailed Certificate of Analysis (COA) documenting purity, identity, and biological activity is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated at -80°C. Allow the vial to reach room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 5.0%
Biological Activity (Cell-Based Assay)	Stimulates antigen-specific T-cell proliferation
Endotoxin Level (LAL)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.