Description

Satumomab Pendetide is a diagnostic radiopharmaceutical agent, specifically a monoclonal antibody fragment conjugated to a chelator. This compound is critical for targeted imaging in nuclear medicine, enabling precise localization of specific cell types within the body. It is primarily utilized by pharmaceutical manufacturers, clinical research organizations, and diagnostic imaging centers for the development and production of advanced diagnostic kits.

Application

• Diagnostic Imaging Agent: Key component in the formulation of radiopharmaceuticals for cancer detection and staging.
• Clinical Research: Used as a reference standard or active pharmaceutical ingredient (API) in oncology and immunology research studies.
• Pharmaceutical Development: Serves as a critical intermediate in the synthesis and quality control of monoclonal antibody-based diagnostic products.
• Nuclear Medicine: Employed in the preparation of technetium-99m (99mTc) labeled kits for immunoscintigraphy procedures.

Basic Information

Product Name	Satumomab Pendetide
CAS No.	138955-26-7
Molecular Formula	C~2200H~3400N~580O~680S~40
Molecular Weight	~50 kDa (Approximate, for the Fab' fragment-chelate conjugate)
Synonyms	OncoScint CR103; OncoScint; Indium In-111 satumomab pendetide; Anti-TAG-72 monoclonal antibody Fab' fragment, pendetide conjugate; IMMU-4; Mab-4; 111In-satumomab pendetide; Technetium Tc 99m satumomab pendetide
EINECS	Contact for details

Quality Control

Our Satumomab Pendetide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and consistency. A detailed Certificate of Analysis (COA) is provided, which includes specifications for appearance, protein concentration, immunoreactivity, radiochemical purity (for labeled forms), and sterility/endotoxin levels where applicable. We adhere to cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized (freeze-dried) material at -20°C or below. Reconstituted solutions should be used immediately or stored as directed for the specific diagnostic kit formulation. Store in a dry environment.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Protein Content (UV)	≥ 95% of label claim
Purity (SEC-HPLC)	≥ 95.0% (Monomeric Fab' conjugate)
Immunoreactivity	≥ 70% binding to specific antigen
Residual Moisture (KF)	≤ 3.0%
Bacterial Endotoxins	< 5.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.