Description

Phenylalanine-Specific Permease, E Coli is a specialized membrane transport protein derived from *Escherichia coli* that facilitates the selective uptake of the essential amino acid L-phenylalanine. This product matters for researchers and developers in the life sciences as it is a critical tool for studying amino acid transport mechanisms, membrane protein function, and bacterial metabolism. It is primarily needed by biotechnology and pharmaceutical companies engaged in metabolic engineering, synthetic biology, and the development of novel microbial production platforms for high-value compounds.

Application

• Biochemical Research: Fundamental studies on amino acid transport kinetics, substrate specificity, and protein structure-function relationships.
• Metabolic Engineering: Integration into microbial chassis to enhance or alter phenylalanine uptake for optimized production of phenylalanine-derived compounds.
• Synthetic Biology: A key functional module in the design of synthetic cellular systems with controlled nutrient import capabilities.
• Enzyme & Pathway Characterization: Used in reconstituted systems to characterize the role of specific transport in overall metabolic flux and pathway efficiency.
• Drug Discovery Target: Investigation as a potential target for novel antibacterial agents that disrupt essential nutrient acquisition in pathogenic bacteria.
• Biosensor Development: Potential component in the development of biosensors for detecting phenylalanine or related metabolites.

Basic Information

Product Name	Phenylalanine-Specific Permease, E Coli
CAS No.	138881-74-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PheP Permease; L-Phenylalanine transporter PheP; Aromatic amino acid permease AroP; Transporter protein PheP; High-affinity phenylalanine-specific permease; EC 138881-74-0; *E. coli* phenylalanine permease
EINECS	Contact for details

Quality Control

Our Phenylalanine-Specific Permease, E Coli is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and biological activity. Each lot is characterized for functional activity and purity relevant to research-grade biological reagents. A comprehensive Certificate of Analysis (COA) detailing specific activity, purity assessment, and buffer composition is provided with every shipment to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent moisture uptake.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Functional Assay)	Confirms phenylalanine transport activity
Purity (SDS-PAGE)	>90%
Specific Activity	Contact for details
Protein Concentration	As per COA
Buffer Composition	Tris-HCl, Glycerol, etc. (see COA)
Biological Contaminants	Tested for absence of significant DNase/RNase activity

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.