Description

Ovalbumin (257-264) Chicken is a defined peptide fragment derived from the chicken egg white protein ovalbumin. This synthetic peptide is a critical research tool for immunology and vaccine development, specifically targeting the SIINFEKL epitope recognized by cytotoxic T-cells. It is essential for scientists and pharmaceutical developers working in immunological research, epitope mapping, and the development of cancer immunotherapies or infectious disease vaccines. The product is supplied as a high-purity lyophilized powder to ensure reliable and reproducible experimental results.

Application

• Immunological Research: A standard antigen for studying MHC class I (H-2Kb) restricted T-cell responses in murine models.
• Vaccine Development: Used as a model antigen in preclinical studies for evaluating novel vaccine platforms and adjuvants.
• T-Cell Activation Assays: Serves as a positive control antigen in ELISPOT, intracellular cytokine staining, and cytotoxicity assays to measure CD8+ T-cell activity.
• Epitope Mapping: Critical for defining and validating minimal cytotoxic T-lymphocyte (CTL) epitopes.
• Cancer Immunotherapy Research: Employed in studies exploring adoptive T-cell transfer and cancer vaccine strategies.
• Quality Control in Immunology: Used to standardize and validate assays across laboratories and production batches of immunoreagents.
• Teaching and Training: A well-characterized tool for academic instruction in advanced immunology and molecular biology techniques.

Basic Information

Product Name	Ovalbumin (257-264) Chicken
CAS No.	138831-86-4
Molecular Formula	C41H62N12O12
Molecular Weight	890.99 g/mol
Synonyms	SIINFEKL Peptide; OVA (257-264); Chicken Ovalbumin Peptide 257-264; H-2Kb-Restricted OVA Peptide; Antigenic Peptide SIINFEKL; OVA257-264; OVA8; Ac-SIINFEKL-NH2 (acetate salt form)
EINECS	Contact for details

Quality Control

Our Ovalbumin (257-264) Chicken is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, correct sequence, and optimal biological activity. Certificates of Analysis (COA) detailing purity by HPLC, mass spectrometry (MS) confirmation, and endotoxin levels are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the lyophilized powder at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption. Solutions should be prepared in appropriate buffers and stored aliquoted at ≤ -20°C to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Sequence	SIINFEKL
Molecular Weight	890.99 ± 1.0 Da
Peptide Content	≥ 70% (by weight)
Solubility	Soluble in water or DMSO
Endotoxin Level	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.