Description

Leucine-Responsive Regulatory Protein CAS NO 138791-20-5 is a specialized regulatory protein that plays a critical role in modulating gene expression in response to leucine availability. This compound is essential for research and development in metabolic engineering and synthetic biology, where precise control of biosynthetic pathways is required. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies focused on amino acid metabolism, bacterial physiology, and the development of novel microbial production platforms.

Application

• Metabolic Pathway Regulation: Used as a key research tool to study and engineer bacterial amino acid biosynthesis, particularly leucine metabolism.
• Synthetic Biology Constructs: Incorporated into genetic circuits and biosensors for the real-time monitoring and control of fermentation processes.
• Pharmaceutical Research: Serves as a target protein for investigating bacterial adaptation and potential antimicrobial strategies.
• Industrial Biotechnology: Applied in the optimization of microbial strains for the high-yield production of branched-chain amino acids and related biochemicals.
• Academic Research: Fundamental studies in prokaryotic gene regulation, signal transduction, and nutritional stress responses.
• Enzyme Activity Studies: Employed in assays to understand allosteric regulation and protein-DNA interaction mechanisms.

Basic Information

Product Name	Leucine-Responsive Regulatory Protein
CAS No.	138791-20-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Lrp Protein; Leucine Regulatory Protein; Leucine-Responsive Transcriptional Regulator; Lrp Transcriptional Regulator; Global Regulator Lrp; Leucine-Responsive Regulatory Protein (E. coli); Leucine-Specific Regulatory Protein; Amino Acid Regulatory Protein Lrp
EINECS	Contact for details

Quality Control

Our Leucine-Responsive Regulatory Protein is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and biological activity. Quality assurance includes analysis for purity, identity, and functional activity using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity (e.g., by SDS-PAGE or HPLC), protein concentration, and functional assay results is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Conforms
Purity (HPLC)	≥ 90%
Protein Content (BCA/Bradford)	≥ 80%
Biological Activity (Gel Shift Assay)	Active
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.