Description

(+)-cis-2(R),3(S)-2,3-Dihydroxy-2,3-Dihydrobenzonitrile is a high-purity chiral dihydroxy nitrile compound, serving as a critical synthetic intermediate and building block in advanced organic chemistry. Its defined stereochemistry and functional groups make it a valuable precursor for the synthesis of complex, optically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals requiring precise stereocontrol.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, especially in antiviral, anticancer, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Asymmetric Catalysis: Serves as a ligand precursor or a chiral auxiliary in catalytic reactions to induce enantioselectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and stereochemistry at universities and corporate R&D centers.

Basic Information

Product Name	(+)-cis-2(R),3(S)-2,3-Dihydroxy-2,3-Dihydrobenzonitrile
CAS No.	138769-96-7
Molecular Formula	C7H7NO2
Molecular Weight	137.14 g/mol
Synonyms	(+)-cis-2,3-Dihydroxy-2,3-dihydrobenzonitrile; (2R,3S)-2,3-Dihydroxy-2,3-dihydrobenzonitrile; (1R,2S)-1,2-Dihydroxy-1,2-dihydro-2-cyanobenzene; Benzonitrile, 2,3-dihydro-2,3-dihydroxy-, (2R-cis)-; cis-(+)-2,3-Dihydroxyindane-1-carbonitrile; (2R,3S)-2,3-Dihydroxyindoline-1-carbonitrile; AR-A 00000489; AR-A00000489
EINECS	Contact for details

Quality Control

Our (+)-cis-2(R),3(S)-2,3-Dihydroxy-2,3-Dihydrobenzonitrile is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.