Description

Pc Protein, Borrelia Burgdorferi is a recombinant protein derived from the causative agent of Lyme disease, Borrelia burgdorferi. This high-purity antigen is critical for the development and quality control of sensitive and specific diagnostic immunoassays. It is primarily utilized by manufacturers and research institutions in the in-vitro diagnostics (IVD), biomedical research, and vaccine development sectors to ensure accurate detection and study of Lyme borreliosis.

Application

• Key Antigen for Lyme Disease Diagnostic Kits: Used as a core coating or detection antigen in ELISA, Western Blot, and lateral flow assays.
• Immunoassay Standard and Control: Serves as a reference standard for calibrating assays and as a positive control material.
• Antibody Production and Purification: Employed to immunize animals for generating specific polyclonal or monoclonal antibodies.
• Biomedical Research: Essential for studying host-pathogen interactions, immune response mechanisms, and the pathogenesis of Lyme disease.
• Vaccine Research and Development: Investigated as a potential vaccine candidate or for evaluating vaccine efficacy.
• Specificity Testing: Used to validate the specificity of diagnostic antibodies and to rule out cross-reactivity with other pathogens.

Basic Information

Product Name	Pc Protein, Borrelia Burgdorferi
CAS No.	138756-96-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Borrelia burgdorferi Pc Protein; Recombinant B. burgdorferi Pc Protein; Lyme Disease Antigen Pc; B. burgdorferi Recombinant Protein; Outer Surface Protein C (OspC) variant; Diagnostic Grade OspC; Borrelia burgdorferi sensu stricto Antigen; Bb Pc Antigen
EINECS	Contact for details

Quality Control

Our Pc Protein, Borrelia Burgdorferi is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation by immunoblotting or mass spectrometry, and functionality testing in relevant immunoassay formats. A comprehensive Certificate of Analysis (COA) detailing purity, endotoxin levels, concentration, and biological activity is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Upon reconstitution, aliquot and store at -70°C to -80°C to minimize freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (Immunoblot)	Positive reaction with specific anti-B. burgdorferi antibodies
Purity (SDS-PAGE)	≥ 95%
Protein Content (BCA/A280)	≥ 90% of total weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (ELISA)	Reactivity confirmed vs. reference standard
Solubility	Soluble in appropriate aqueous buffers (e.g., PBS)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.