Description

Pentetreotide is a synthetic somatostatin analog peptide with high affinity for somatostatin receptors. This compound is a critical intermediate and reference standard in the development and quality control of radiopharmaceuticals, particularly for diagnostic imaging and targeted radiotherapy. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on oncology and neuroendocrine tumor diagnostics. Pentetreotide CAS NO 138661-02-6 serves as the foundational molecule for the preparation of radiolabeled agents like Indium-111 Pentetreotide.

Application

• Radiopharmaceutical Precursor: Primary starting material for the synthesis of radiolabeled diagnostic agents (e.g., 111In-Pentetreotide).
• Oncology Research: Used in the study and imaging of somatostatin receptor-positive tumors, such as neuroendocrine tumors (NETs).
• Reference Standard: Serves as a high-purity chemical reference standard (CRS) for analytical method development and quality control in pharmaceutical manufacturing.
• Peptide Synthesis Intermediate: Key building block in the research-scale synthesis of novel somatostatin analog conjugates.
• Diagnostic Kit Formulation: An active pharmaceutical ingredient (API) in the preparation of cold kits for radiopharmacy use.
• Biomarker Development: Utilized in the development of assays and probes for receptor targeting and molecular imaging.

Basic Information

Product Name	Pentetreotide
CAS No.	138661-02-6
Molecular Formula	C65H95N17O19S2
Molecular Weight	1434.7 g/mol
Synonyms	DTPA-Phe-Octreotide; DTPA-D-Phe1-Octreotide; Pentetreotide (INN); DTPA-Octreotide; (DTPA0,D-Phe1)-Octreotide; Nα-(DTPA)-D-Phenylalanyl1-Octreotide; SMT 487; Octreoscan precursor
EINECS	Contact for details

Quality Control

Our Pentetreotide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the product should be handled under anhydrous conditions and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Total Peptide Content)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	Reported

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.