Description

Imciromab Pentetate is a diagnostic radiopharmaceutical agent, specifically a monoclonal antibody fragment conjugated with pentetate. This compound is critical for targeted imaging in nuclear medicine, enabling precise localization and diagnosis. It is primarily utilized by pharmaceutical manufacturers, radiopharmacies, and clinical research organizations developing and producing advanced diagnostic kits for cardiovascular and oncological applications.

Application

• Myocardial Infarction Imaging: As a technetium-99m (99mTc) labeled agent for the scintigraphic detection of acute myocardial infarction.
• Diagnostic Kit Formulation: A key active pharmaceutical ingredient (API) in the manufacture of ready-to-label diagnostic kits for hospitals and clinics.
• Cardiac Research: Used in preclinical and clinical research studies to investigate cardiac necrosis and the efficacy of therapeutic interventions.
• Radiopharmaceutical Development: Serves as a model compound in the research and development of new antibody-based diagnostic imaging agents.
• Quality Control Reference Standard: Employed as a reference standard in analytical laboratories to ensure the purity and performance of commercial diagnostic products.

Basic Information

Product Name	Imciromab Pentetate
CAS No.	138660-99-8
Molecular Formula	C225H346N58O103
Molecular Weight	Approx. 5070 g/mol
Synonyms	Imciromab Pentetate; Antimyosin Fab, Technetium Tc 99m-Labeled; Technetium Tc 99m Imciromab; Tc-99m Imciromab; Myoscint™ (brand name); Technetium (99mTc) antimyosin monoclonal antibody Fab fragment; Centoxin (historical context); HA-1A Fab fragment-pentetate
EINECS	Contact for details

Quality Control

Our Imciromab Pentetate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to ensure it meets exacting standards for radiopharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under controlled, dry conditions to maintain stability. Allow the sealed vial to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Purity (Related Substances)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Bacterial Endotoxins	< 1.0 EU/mg
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.