Description

3-Fluoro-α-Methyl-4-(5-Methyl-2-Thiazolyl)Benzeneacetic Acid is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate of significant commercial and research interest. This compound is a critical building block in the synthesis of advanced pharmaceutical agents, particularly those targeting inflammation and pain. It is essential for R&D chemists and manufacturers in the pharmaceutical industry developing next-generation therapeutic compounds.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor for novel NSAID (Non-Steroidal Anti-Inflammatory Drug) candidates.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety in the research and development of new analgesic and anti-inflammatory agents.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate cyclooxygenase (COX) enzyme inhibition pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and structure-activity relationship (SAR) studies.

Basic Information

Item	Detail
Product Name	3-Fluoro-α-Methyl-4-(5-Methyl-2-Thiazolyl)Benzeneacetic Acid
CAS No.	138568-74-8
Molecular Formula	C₁₃H₁₂FNO₂S
Molecular Weight	265.30 g/mol
Synonyms	3-Fluoro-α-methyl-4-(5-methyl-2-thiazolyl)benzeneacetic acid; 2-[3-Fluoro-4-(5-methyl-1,3-thiazol-2-yl)phenyl]propanoic acid; Flumizole intermediate; α-Methyl-3-fluoro-4-(5-methyl-2-thiazolyl)benzeneacetic acid; 4-(5-Methyl-2-thiazolyl)-3-fluoro-α-methylbenzeneacetic acid; 2-(3-Fluoro-4-(5-methylthiazol-2-yl)phenyl)propanoic acid; CAS 138568-74-8
EINECS	Contact for details

Quality Control

Our 3-Fluoro-α-Methyl-4-(5-Methyl-2-Thiazolyl)Benzeneacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.