Description

Cyclopropanecarboxylic Acid, 1-Amino-2-Ethyl-, Methyl Ester, (1R-Cis)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly in the pharmaceutical sector. It is primarily needed by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereochemistry is critical for efficacy. The product is supplied under strict quality control to ensure batch-to-batch consistency for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and production of novel drug candidates, especially in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereoisomers exhibit enhanced biological activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new chiral catalysts and methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances.
• Process Chemistry & Scale-Up: Provides a reliable starting point for optimizing synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-Ethyl-, Methyl Ester, (1R-Cis)- (9Ci)
CAS No.	138457-96-2
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(1R,2S)-1-Amino-2-ethylcyclopropanecarboxylic acid methyl ester; Methyl (1R,2S)-1-amino-2-ethylcyclopropanecarboxylate; (1R-cis)-1-Amino-2-ethylcyclopropanecarboxylic Acid Methyl Ester; cis-1-Amino-2-ethylcyclopropanecarboxylic acid methyl ester; 1-Amino-2-ethylcyclopropanecarboxylic acid methyl ester, (1R-cis)-; Chiral cyclopropane amino ester; Ethyl cyclopropane amino acid methyl ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Amino-2-Ethyl-, Methyl Ester, (1R-Cis)- (9Ci) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.