Description

Hemoglobin Cleveland is a specific, well-characterized form of hemoglobin, a vital oxygen-transporting metalloprotein found in red blood cells. This high-purity biochemical is essential for research and development in life sciences, providing a critical reference standard for studying hemoglobin structure, function, and related pathologies. It is primarily utilized by pharmaceutical R&D teams, diagnostic manufacturers, and academic research institutions focused on hematology, biochemistry, and therapeutic development for blood disorders.

Application

• Biochemical Research Standard: Serves as a purified reference material for spectroscopic studies, oxygen-binding kinetics, and protein stability research.
• Diagnostic Reagent Development: Used in the formulation and calibration of clinical diagnostic assays for hemoglobin analysis and blood gas testing.
• Pharmaceutical R&D: Acts as a model compound in the development of blood substitutes, oxygen carriers, and therapies for sickle cell disease or thalassemia.
• Quality Control in Biomanufacturing: Employed as a control standard in processes involving hemoglobin or heme proteins to ensure product consistency and purity.
• Educational & Analytical Use: Provides a high-quality substrate for teaching advanced biochemistry concepts and for use in analytical method validation.

Basic Information

Product Name	Hemoglobin Cleveland
CAS No.	138341-54-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb Cleveland; Hemoglobin (Cleveland); Human Hemoglobin Variant Cleveland; Unstable Hemoglobin Cleveland; Hemoglobin β99 (G1) Asp→Tyr; Hemoglobin β99 Asp→Tyr; HBB: c.296G>T (p.Asp99Tyr)
EINECS	Contact for details

Quality Control

Our Hemoglobin Cleveland is produced and handled under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including purity assay and identity confirmation, to ensure it meets the exacting standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider keeping the product desiccated at -20°C.

Specification

Item	Specification
Appearance	Dark red to brown lyophilized powder
Identification (IR / HPLC)	Conforms to Standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Methemoglobin Content	≤ 5%
Solubility	Clear solution in buffer
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.