Description

Hemoglobin A(2) Niigata is a highly purified, standardized reference material of the A2 variant of human hemoglobin. This compound is critical for the calibration and validation of diagnostic assays and research methodologies. It is primarily utilized by clinical diagnostics manufacturers, pharmaceutical R&D laboratories, and academic research institutions focused on hemoglobinopathies and blood-related disorders.

Application

• Reference Standard for Clinical Diagnostics: Calibration and quality control material for HPLC, capillary electrophoresis, and other analytical systems used in the detection and quantification of Hemoglobin A2 for diagnosing β-thalassemia trait.
• Biochemical Research: Study of hemoglobin structure, function, and stability, particularly comparative studies between HbA and HbA2.
• Assay Development & Validation: Essential component in the development and validation of new in-vitro diagnostic (IVD) devices and kits for hemoglobin variant analysis.
• Pharmaceutical Testing: Used in research related to therapeutic agents targeting sickle cell disease and other hemoglobin disorders.
• Manufacturing Control: Serves as a process control standard in the production of diagnostic reagents and calibrators.
• Proficiency Testing: Material for external quality assessment (EQA) schemes and laboratory accreditation programs.

Basic Information

Product Name	Hemoglobin A(2) Niigata
CAS No.	138341-53-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb A2; Hemoglobin A2; Hemoglobin δ2β2; Delta2-Beta2 Globin Tetramer; Hemoglobin Variant A2; Human Hemoglobin A2; CAS 138341-53-4; Hemoglobin A₂ (Niigata)
EINECS	Contact for details

Quality Control

Our Hemoglobin A(2) Niigata is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assay by HPLC and identity confirmation, to ensure it meets the exacting standards required for diagnostic and research applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term stability, consider storage at -20°C.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Solubility	Soluble in water or buffer
Moisture Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.