Description

Nebacumab CAS NO 138330-99-1 is a monoclonal antibody specifically developed for therapeutic applications. This compound is of significant interest in the pharmaceutical and biotechnology sectors for its targeted biological activity. It is primarily utilized in advanced research and development for novel treatment strategies, making it essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on immunology and critical care medicine.

Application

• Primary application in pharmaceutical research and development for targeted therapies.
• Key ingredient in pre-clinical and clinical studies investigating treatments for severe infections.
• Used as a reference standard in bioanalytical method development and quality control laboratories.
• Critical component in the formulation of investigational new drugs (INDs) for regulatory submissions.
• Employed in biopharmaceutical manufacturing process development and optimization.
• Utilized for academic and institutional research in immunology and monoclonal antibody mechanisms.

Basic Information

Product Name	Nebacumab
CAS No.	138330-99-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HA-1A; Human Anticore Monoclonal Antibody; Anti-Lipid A Monoclonal Antibody; Centoxin (former trade name); Nebacumab (INN); Monoclonal Antibody HA-1A; E5 Antibody (related); Anti-Endotoxin Monoclonal Antibody
EINECS	Contact for details

Quality Control

Our Nebacumab is produced and tested under stringent quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety, adhering to relevant guidelines for biopharmaceutical intermediates. Certificates of Analysis (COA) documenting critical quality attributes are available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at the recommended temperature (typically 2-8°C for long-term stability). Due to its hygroscopic (moisture-sensitive) nature, protect from exposure to high humidity. For specific storage and handling instructions, refer to the material safety data sheet (MSDS) or technical data sheet.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/LC-MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Protein Content (UV/A280)	As per COA
Biological Activity (if applicable)	As per COA
Endotoxin (LAL)	< 10.0 EU/mg
Sterility (Membrane Filtration)	Sterile
Moisture Content (Karl Fischer)	< 5.0% (for lyophilized form)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.